In the James Cameron blockbuster 'Avatar,' 3-D cinematography is the real star. The bugs and crawling creatures seem to slither into the theater seats. The floating mountains of the planet Pandora hover gloriously overhead. And the Na'Vi, Pandora's 10-foot-tall, blue-skinned natives, come convincingly to life.

I want to do stories that are about the bits of cultural furniture that are sitting there that we're like, 'Oh yeah, that's been there for years! What could possibly be weird about it?' And then we're going to lift that piece of furniture and look at all the bugs scurry away.

Going on safari in South Africa was hardcore but a lot of fun - though my friend Maura was absolutely freaking out about all the bugs in her hair and having to pee in the sand.

You know my girls are so funny. You're out in the country and there are critters everywhere and they get a little like, 'Oh my God! Oh no, bugs!' and I had to say, 'Honey this is fine. This is their world and it's all part of being in the country.' I realized, 'Oh my God, my girls are really city girls.'

I certainly wasn't the kind of kid that grew up collecting bugs and spiders.

I had bedbugs in 2005. I felt like a leper. Worse than a leper. At least lepers had a colony they could go and live in with other people who empathized. I instead had friends stand up from tables and walk out of restaurants when I told them I had bedbugs, because they were afraid I'd transfer the bugs to them.