The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
To develop drugs for people, we basically dismantle the system. In the lab, we look at things the size of a cell or two. We dismantle life into very small models.
The scale of time for a politician runs between one primary and the next, and in Israel, this means two to three years because elections almost never take place once every four years as stipulated by law. The timetable for a system of research is completely different.
Your belief system saturates the space around you.
As we get more transparent with data sets about infrastructure and systems management, I have a feeling we'll see big changes in how we think about complexity and our relationship to our actions.
If you think about the market that we're in, and more broadly just the enterprise software market, the kind of transition that's happening right now from legacy systems to the cloud is literally, by definition, a once-in-a-lifetime opportunity.
All of a sudden, if you think about the entire ecosystem of connected devices that can pull down information, access content and allow me to share and work and communicate, the vast majority now are not Windows computers. They are iPhones. They are iPads. They are Android devices.
I consider myself an inventor first and an entrepreneur second. In real life, my hero is Thomas Edison. He was a great inventor, but also an outstanding entrepreneur who was able to sell his inventions to the masses. He didn't just develop the light bulb; he invented the entire electric grid and power distribution system.
When I was 8 or 9, I started using bulletin board systems, which was the precursor to the Internet, where you'd dial into... a shared system and shared computers. I've had an email address since the late '80s, when I was 8 or 9 years old, and then I got on the Internet in '93 when it was first starting out.
The original idea before Mint was a life and goal planning system I called Carpe Viva. The idea was that all of life's goals, from buying a house, getting an MBA, or learning Spanish could be quantified in both time and money.
