I think the best comedy enlightens, informs, and changes the way people look at the world.

Well, filming in Hawaii, you know, is a blessing. It's one of the most beautiful places on this planet. It has a very mystic energy which informs you as an actor.

In 'Gravity,' nearly everything is a metaphor for the main character. The way I tend to approach a film is that character and background are equally important; one informs the other. Here, Sandra Bullock is caught between Earth and the void of the universe, just floating there in between. We use the debris as a metaphor for adversity.

The working class of England take their deracination completely for granted. Disenchantment is the happy code that informs every byway of the underclass: service jobs, celebrity dreams, Lotto wins, leisured poverty on pre-crunch credit cards, it's all there, part of the story of an English people whose grandparents never had it so good.

Our understanding of how DNA informs our health and development is advancing at an incredible pace.

Whereas in the past people have seen the two sexes as almost incomprehensibly different, now there is a group of people that are explaining the connections between both the genders, literally in the way their biology informs some of their expression.

I have the advantage of many perspectives as someone who has lived in different kinds of communities: as a woman, as someone who previously identified as a lesbian, as someone who is a person of color. I've had a lot of life, so that informs what I do.