The smartphone revolution is under-hyped, more people have access to phones than access to running water. We've never had anything like this before since the beginning of the planet.

Many of the best firms historically in venture capital have been multi-sector.

People tend to think of the web as a way to get information or perhaps as a place to carry out e-commerce. But really, the web is about accessing applications.

There's a new generation of entrepreneurs in the Valley who have arrived since 2000, after the dotcom bust. They're completely fearless.

More and more major businesses and industries are being run on software and delivered as online services - from movies to agriculture to national defense.

Aaron Sorkin was completely unable to understand the actual psychology of Mark or of Facebook. He can't conceive of a world where social status or getting laid or, for that matter, doing drugs, is not the most important thing.

People are so bad at driving cars that computers don't have to be that good to be much better. Any time you stand in line at the D.M.V. and look around, you're like, Oh, my God, I wish all these people were replaced by computer drivers.

Any new technology tends to go through a 25-year adoption cycle.

On the back end, software programming tools and Internet-based services make it easy to launch new global software-powered start-ups in many industries - without the need to invest in new infrastructure and train new employees.

Whatever you're selling, storage or networking or security, you're going head to head with the incumbent players.

The reality is the world is a really, really big place, and there's a lot of people running around with a lot on their mind. And you really have to figure out how to build a company that can put on a message that can actually reach people and have an impact globally.

To bring out a new technology for consumers first, you just had a very long road to go down to try to find people who actually would pay money for something.

Consumers are freeing up an enormous amount of time that they were spending with stereotypical old media, and clearly, that time is going primarily two places: videogames and online.

I think the tech stock, the public market is still completely traumatized by the dotcom crash. I think the investors and reporters and analysts and everybody is determined to not get taken advantage of again, and that is what everybody who lived through 2000, what they kind of remember.

One of the big first computers was called SAGE, which was a missile defense, the first missile-defense computer, which was, like, one of the first computers in the history of the world which got sold to the Department of Defense for, I don't know, tens and tens of millions of dollars at the time.

Companies in every industry need to assume that a software revolution is coming.